The list of polluting substances in industrial sewage of non-ferrous metals ores enrichment is given in article. Clearing of such waters up to effective standards cannot be made in the absence of cheap effective methods, therefore the best way of prevention of water objects pollution is transfer of the enterprises on system of recycling water supply. Various stages of this problem solving with using various methods and techniques are described. As a result, the scientifically-proved technology of recycling water supply of enrichment of most complicated non-ferrous metals ores — polymetallic has been developed. Some conditions for realization of internal-drainage water supply for concentration plants are formulated. Simultaneously perfection of technology of non-ferrous metals ores enrichment with application of hydrophobic interactions is conducted. These researches in the conditions of recycling water supply are prolonged.